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基于分数生成模型的投影数据补全研究

Projection completion based on score-based generative model

  • 摘要: 目的 散射校正是锥束CT 重建中的一个关键问题, 有效抑制散射能够显著提升图像质量。 射线阻挡装置是一种被公认的有效散射校正方法, 在实际应用中起着至关重要的作用。 然而, 该装置在去除散射线的同时也会遮挡原始射线, 导致投影数据的缺失, 从而降低重建质量。本研究旨在利用生成模型有针对性地补全缺失的投影数据, 以提高重建质量。 方法 使用分数生成模型对扫描对象进行训练, 学习重建对象的图像分布特征。 在多个时间步骤的采样过程中, 结合域变换, 将生成的图像信息转换到投影域。 通过已知投影与生成投影的加权求和, 再进行域变换回到图像域, 进行下一步采样, 获得最终重建图像。 结果 本研究针对射线阻挡装置中投影的缺失问题进行投影补全, 提供了新思路。 并使用两个独立的数据集进行了初步的验证。 结论 本研究提出了一种结合分数生成模型的投影补全算法, 在射线阻挡装置造成较大的投影缺失时, 可以对缺失的投影进行补全, 提高图像的质量。

     

    Abstract: Purpose Scatter correction is a critical issue in cone-beam CT reconstruction, as effective scatter suppression can significantly enhance image quality. The beam stop array (BSA) is a well-established scatter correction method that plays a vital role in practical applications. However, while removing scattered rays, the BSA also obstructs primary rays, leading to missing projection data and consequently degrading reconstruction quality. This study aims to leverage generative models to specifically restore missing projection data, thereby improving reconstruction quality. Methods A score-based generative model was employed to train on scanned objects, learning the image distribution characteristics of the reconstructed subject. During multi-step sampling, domain transformation was integrated to convert generated image information into the projection domain. A weighted summation of known projections and generated projections was performed, followed by inverse domain transformation back to the image domain for subsequent sampling, ultimately yielding the final reconstructed image. Results This study proposes a novel approach for projection completion to address missing data caused by the BSA, with preliminary validation conducted on two independent datasets. Conclusion The proposed projection completion algorithm, incorporating a score-based generative model, demonstrates the capability to effectively restore missing projections in scenarios where the BSA induces significant data loss, thereby enhancing overall image quality.

     

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